Dr. Suresh Chaware (Plastic, Microvascular and Hair transplant Surgeon) and the team at VIMS Hospital, and Saundarya City, hair transplant and plastic surgery centre, Nagpur, performed a very rare surgery called vascularized lymph node transfer for treatment of lymphedema also known as elephantiasis this is the first case in central India.

Retired bank teller turns her breast cancer journey and subsequent lymphedema diagnosis into a mission and organization to help others.

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Reseachers have made an important discovery how mutations in a novel gene, ANGPT2, cause a lymphatic disease called primary lymphedema. Discovery is essential for the proper diagnosis of patients suffering from primary lymphedema.

The Human Molecular Genetics laboratory of the de Duve Institute (UCLouvain), headed by Professor Miikka Vikkula, recently identified mutations in a novel gene, ANGPT2, responsible for primary lymphedema. Together with the Wihuri Research Institute and it's director Professor Kari Alitalo at the University of Helsinki, Finland, the laboratories could show how these mutations cause the disease.

Surgery may be a way to reduce the risk for lymphedema, a chronic and potentially devastating condition that approximately 40% of breast cancer patients at highest risk for it will develop. The surgery does initially increase operating time, but this decreases as surgeons gain experience, according to new research.

At Cleveland Clinic in Ohio, lymphedema prevention surgery (LPS), defined as immediate lymphatic reconstruction at the time of axillary dissection, consists of several components performed by either the breast surgeon or reconstructive surgeon.

What is lymph?
Lymphatic drainage massage is the draining of lymph fluid that might cause swelling—you might see it as puffy eyes or swollen arms and legs. This condition, known as lymphoedema, usually occurs as a result of a build-up of lymph fluid, which is a yellow fluid that flows through the lymphatic systems. However unlike blood vessels that have a heart to pump the fluid evenly around the body, lymph vessels do not have a pump. Instead, they rely on the blood vessels to facilitate movement. The fluid is part of the immune system, transporting nutrients and oxygen to cells and flushing out toxins via the kidney.

A 61-year-old woman presented to her family physician’s office with long-standing bilateral leg swelling. She voiced that her legs had become “heavy” and that the skin was “thick” and “burning.” She had started using a cane for gait instability.

An insidious onset of swelling in her left lower leg had started more than 25 years earlier without any obvious cause. A diuretic was initially prescribed; however, the swelling progressed. The patient was subsequently prescribed various diuretic dosing regimens, with minimal improvement. The diuretic was eventually stopped 3 years before the current presentation.

Over the years, the patient’s right lower leg had also begun to swell. She had undergone venous Doppler ultrasonography of the peripheral extremities 16 years earlier to rule out venous pathologies and was evaluated for liver disease and congestive heart failure. The results of the investigations were negative.

The patient’s medical history included overactive bladder and osteoarthritis. She had no history of coronary artery disease, venous thrombosis or liver disease. There was no family history of lymphedema. She was taking solifenacin 5 mg/d for overactive bladder and a calcium supplement.

On physical examination, the patient had bilateral nonpitting leg edema (Figure 1). The left lower leg was larger than the right, and the ankle anatomy was obscured on visual inspection. The skin of both lower legs was thick and rigid on palpation, with deep skin creases and areas of hyperkeratosis, and there was mycosis of the left first toenail. Stemmer sign (Box 1) was positive. There were no signs of venous thrombosis. Bilateral leg ultrasonography showed normal and competent peripheral veins.

Advanced pneumatic compression devices (APCD) were safe and effective for the treatment of lymphedema caused by head and neck cancer (HNC), according to results from a randomized, wait-list controlled study published in Supportive Care in Cancer.

LOS ANGELES, Calif. (Ivanhoe Newswire) — There are more than 3.5 million breast cancer survivors in the U.S. One in five of those will be diagnosed with lymphedema. It’s a painful swelling usually in one or both arms. There’s a new super-microsurgical procedure that may prevent it.

Veda Jackson, breast cancer survivor, picked up crocheting about a year ago. She got needles and yarn and got hooked! It took her mind off her diagnosis.

“I was diagnosed with stage three metastasis, breast cancer because it had spread to my lymph nodes,” Jackson told Ivanhoe.

Jackson was at risk of developing lymphedema after having a mastectomy and 13 lymph nodes removed.